Cathepsin S and cathepsin L in serum and synovial fluid in rheumatoid arthritis with and without autoantibodies
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چکیده
منابع مشابه
Cathepsin S and cathepsin L in serum and synovial fluid in rheumatoid arthritis with and without autoantibodies.
OBJECTIVES Cathepsin S and cathepsin L are endosomal proteolytic enzymes involved in the degradation of extracellular matrixes, angiogenesis and antigen presentation. Cathepsins could thus play several roles in the disease process of RA. The aim of this study was to examine differences in cathepsin S and cathepsin L levels in serum and SF of RA patients with and without ACPA and RF. METHODS I...
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Rheumatoid factors (RF) are autoantibodies with specificity for the Fc portion of human IgG. Production of RF is a characteristic feature of rheumatoid arthritis (RA) and is detectable in high titer in about 90% of these patients. In this study, we measured total IgM, IgA, IgMRF and IgARF in serum and synovial fluid of 45 RA patients by ELISA and the results were compared with those obtained b...
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چکیده ندارد.
Increased IL-33 in Synovial Fluid and Paired Serum Is Associated with Disease Activity and Autoantibodies in Rheumatoid Arthritis
OBJECTIVES IL-33, a newly found cytokine which is involved in joint inflammation, could be blocked by a decoy receptor-sST2. The expression and correlation of IL-33 and sST2 in rheumatoid arthritis (RA) are of great interest. METHODS Synovial fluid (SF) was obtained from 120 RA and 30 osteoarthritis (OA) patients, and paired sera were collected from 54 of these RA patients. The levels of IL-3...
متن کاملcomparative measurement of rheumatoid factor in serum and synovial fluid of rheumatoid arthritis patients by elisa and latex-agglutination test
rheumatoid factors (rf) are autoantibodies with specificity for the fc portion of human igg. production of rf is a characteristic feature of rheumatoid arthritis (ra) and is detectable in high titer in about 90% of these patients. in this study, we measured total igm, iga, igmrf and igarf in serum and synovial fluid of 45 ra patients by elisa and the results were compared with those obtained by...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2015
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/keu486